南京地区32家医院2012-2014年抗血小板药和抗凝血药使用分析
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篇名: 南京地区32家医院2012-2014年抗血小板药和抗凝血药使用分析
TITLE:
摘要: 目的:为抗血小板药和抗凝血药临床合理使用提供参考。方法:采用回顾性研究方法,对南京地区32家医院2012-2014年抗血小板药和抗凝血药的销售金额、用药频度(DDDs)、日均费用(DDC)等进行统计和分析。结果:南京地区32家医院共涉及23种抗血小板药和抗凝血药,药品销售金额呈逐年增长趋势;销售金额各年均排前3位的是氯吡格雷、低分子肝素和红花;DDDs各年均排前3位的是氯吡格雷、华法林和低分子肝素;华法林、肝素和噻氯匹啶的DDC<10元;氯吡格雷和利伐沙班的B/A值等于或最接近1,西洛他唑、舒洛地特、蚓激酶、华法林、沙格雷酯、脉络舒通、替格瑞洛和噻氯匹啶的B/A值>1。结论:南京地区32家医院2012-2014年抗血小板药和抗凝血药临床应用基本合理,氯吡格雷、华法林、低分子肝素和肝素占主导地位,替格瑞洛、阿哌沙班、达比加群酯的临床应用前景可观。
ABSTRACT: OBJECTIVE: To provide refereuce for rational use of antiplatelet and anticoagulant drugs. METHODS: In retrospective study, the application of antiplatelet and anticoagulant drugs in 32 hospitals from Nanjing area was analyzed statistically in respects of consumption sum, DDDs, DDC, etc. RESULTS: A total of 23 kinds of antiplatelet and anticoagulant drugs were used in 32 hospitals from Nanjing area, and consumption sum increased year by year. Top 3 drugs in the list of consumption sum always were clopidogrel, low molecular weight heparin and Carthamus tinctorious. Top 3 drugs in the list of DDDs were clopidogrel, warfarin and low molecular weight heparin. DDC of warfarin, heparin and ticlopidine was less than 10 yuan; B/A values of clopidpgrel and rovarpxabam were equal to or close to 1; On the other hand, the B/A values of cilostazol, sulodexide, PPA, warfarin, sarpogrelate, mailuo shutong, ticagrelor and ticlopidine were all more than 1. CONCLUSIONS: The antiplatelet and anticoagulant drugs are used rationally in 32 hospitals from Nanjing area; clopidogrel, warfarin, low molecular weight heparin and heparin dominated; ticagrelor, apixaban and dabigatran etexilate is promising in the future.
期刊: 2016年第27卷第11期
作者: 潘海燕,刘慧,许静洁,蔡静
AUTHORS: PAN Haiyan,LIU Hui,XU Jingjie,CAI Jing
关键字: 抗血小板药;抗凝血药;用药分析;南京地区
KEYWORDS: Antiplatelet drugs; Anticoagulant drugs; Analysis of drug use; Nanjing area
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