SIMPLE药学服务模式在支气管哮喘、COPD患者慢病管理中的实践及效果研究
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篇名: SIMPLE药学服务模式在支气管哮喘、COPD患者慢病管理中的实践及效果研究
TITLE:
摘要: 目的:将SIMPLE药学服务模式应用于支气管哮喘、慢性阻塞性肺疾病(COPD)患者的慢病管理,并评价其效果。方法:以随机抽样法选取2016年9月-2017年6月在苏州大学附属第一医院呼吸科就诊的支气管哮喘、COPD患者200例,采用简单随机法分成对照组(100例)和干预组(100例)。对照组患者予以常规治疗;干预组患者在对照组治疗基础上戒烟、有效使用吸入剂、监控检测指标、正确选择药物、采用科学的生活方式并接受用药宣教。比较两组患者入组时和入组3、6个月后的装置使用评分、肺功能指标[第1秒用力呼气量占预计值的百分比(FEV1%)、第1秒用力呼气占用力肺活量的百分比(FEV1/FVC)]、急性发作/加重患者数、临床有效控制率以及不良反应发生率、装置使用依从性[Morisky用药依从性量表(MMAS-8)评分]。结果:与入组时比较,入组3、6个月后干预组装置使用评分、临床有效控制率、MMAS-8评分显著升高,急性发作/加重≥2次的患者显著减少,差异均有统计学意义(P<0.05)。与对照组比较,入组3、6个月后干预组患者装置使用评分、临床有效控制率、MMAS-8评分、FEV1%显著升高,急性发作/加重≥2次的患者显著减少,差异均有统计学意义(P<0.05)。干预组不良反应发生率显著低于对照组,差异有统计学意义(P<0.05)。结论:采用SIMPLE药学服务模式对支气管哮喘、COPD患者进行慢病管理可提高患者用药依从性和临床疗效,减少不良反应。
ABSTRACT: OBJECTIVE: To adopt SIMPLE pharmaceutical care mode in chronic disease management of bronchial asthma and COPD patients, and to evaluateits the effect. METHODS: By random sampling, a total of 200 bronchial asthma and COPD patients selected from respiration department in the First Affiliated Hospital of Soochow University during Sept. 2016-Jun. 2017 were divided into control group (100 cases) and  intervention group (100 cases) by simple randomization. Control group received routine treatment. Intervention group additionally received education on quitting smoking, effective use of the inhaler, monitoring detection indexes, selecting drugs correctly, scientific life style. Inhaled device scores, lung function indexes (FEV1%, FEV1/FVC), the number of  patients with acute attack/exacerbation, clinical effective control rates, ADR occurrence rates, compliance of using apparatus (MMAS-8 score)were compared between 2 groups before enrollment, 3 and 6 months after enrollment. RESULTS: Commpared with during enrollment, inhaled device score, clinical effective control rate and MMAS-8 score of intervention group incereased significantly 3,6 months after enrollment, while patients with acute attack/exacerbation ≥2 times decreased significantly, with statistical significance (P<0.05). Compared with control group, inhaled device score, clinical effective control rate, MMAS-8 score  and FEV1% of intervention group increased significantly, patients with acute attack/exacerbation ≥2 times decreased significantly 3 and 6 months after enrollment with statistical significance (P<0.05); the ADR occurrence rate was lower than control group,with statistical significance(P<0.05). CONCLUSIONS: Chronic disease management of bronchial asthma and COPD patients with SIMPLE pharmaceutical care mode can improve medication compliance and clinical efficacy, and reduce ADR.
期刊: 2018年第29卷第10期
作者: 陈蓉,周磊,秦琼,宋伟华,包健安
AUTHORS: CHEN Rong,ZHOU Lei,QIN Qiong,SONG Weihua,BAO Jian’an
关键字: 支气管哮喘;慢性阻塞性肺疾病;SIMPLE药学服务模式;慢病管理
KEYWORDS: Bronchial asthma; COPD; SIMPLE pharmaceutical care mode; Chronic disease management
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