术前加用基于西帕依固龈液的牙周基础治疗方案治疗妊娠期牙龈瘤的临床观察
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篇名: 术前加用基于西帕依固龈液的牙周基础治疗方案治疗妊娠期牙龈瘤的临床观察
TITLE:
摘要: 目的:观察术前加用西帕依固龈液的牙周基础治疗方案治疗妊娠期牙龈瘤的临床疗效与安全性。方法:选取2015年1月-2016年1月齐齐哈尔医学院附属第二医院收治的86例妊娠期牙龈瘤患者作为研究对象,采用随机数字表法分为观察组与对照组,各43例。对照组患者根据瘤体大小进行结扎术以及口腔微电刀手术治疗;观察组患者则在术前进行基于西帕依固龈液(含漱3~5 mL,每次2~3 min,每日3~5次,疗程为5 d)的牙周基础治疗,再进行手术治疗。观察两组患者的临床疗效、牙龈相关指标(牙龈指数、龈沟出血指数、牙周探诊深度)、生活质量评分及不良反应、并发症的发生情况,并在治疗后1年随访两组患者牙龈瘤复发情况。结果:研究过程中未见脱落病例。观察组患者的治疗总有效率为97.67%,显著高于对照组的79.07%(P<0.05);治疗后,两组患者的上述牙龈相关指标较治疗前显著下降,生活质量评分较治疗前显著升高,且观察组显著优于对照组(P<0.05)。两组患者治疗过程中均未见严重不良反应或并发症发生。治疗后1年,观察组患者的牙龈瘤复发率为2.33%,显著低于对照组的13.95%(P<0.05)。结论:较之单纯手术治疗,术前加用基于西帕依固龈液的牙周基础治疗方案的临床疗效更佳、复发率更低,且安全性较高。
ABSTRACT: OBJECTIVE: To observe the clinical efficacy and safety of additional use of Cypate gingival fluid in periodontal basic therapy before surgery in the treatment of pregnancy gingival tumor. METHODS: A total of 86 patients with pregnancy gingival tumor in Second Affiliated Hospital of Qiqihar Medical University during Jan. 2015 to Jan. 2016 were divided into observation group and control group according to random number table, with 43 cases in each group. Control group received ligation and oral micro-electrosurgical surgery according to the volume of tumor. Observation group was given Cypate gingival fluid-based periodontal basic therapy (3-5 mL for gargling, 2-3 min each time, 3-5 times each day, 5 d) and then receive surgery. Clinical efficacies, gingival related indexes (gingival index, sulcular bleeding index, probing depth), quality scores of life, ADR, the occurrence of complications were observed in 2 groups. The followed-up was conducted 1 year after surgery, and the recurrence of gingival tumor was compared between 2 groups. RESULTS: No case was found shedding in the study. The total response rate of observation group was 97.67%, which was significantly higher than 79.07% of control group (P<0.05). After treatment, the gingival related indexes of 2 groups were decreased significantly compared to before treatment, while quality scores of life were increased significantly compared to before treatment, observation group was significantly better than control group (P<0.05). No severe ADR or complication was found in 2 groups during treatment. Recurrence rate of gingival tumor in observation group was 2.33%, which was significantly lower than 13.95% in control group 1 year after treatment (P<0.05). CONCLUSIONS: Compared with surgery alone, additional use of Cypate gingival fluid in periodontal basic therapy before surgery has better clinical efficacy and lower recurrence rate, with good safety.
期刊: 2018年第29卷第4期
作者: 邬志锋,徐岩,杨旭,张则明,方丽丽
AUTHORS: WU Zhifeng,XU Yan,YANG Xu,ZHANG Zeming,FANG Lili
关键字: 西帕依固龈液;牙周基础治疗;手术;妊娠期牙龈瘤
KEYWORDS: Cypate gingival fluid; Periodontal basic therapy; Surgery; Pregnancy gingival tumor
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