康复新液联合疮疡灵、明胶海绵对2型糖尿病患者阻生牙拔除术后干槽症发生的影响
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篇名: 康复新液联合疮疡灵、明胶海绵对2型糖尿病患者阻生牙拔除术后干槽症发生的影响
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摘要: 目的:探讨康复新液联合疮疡灵、明胶海绵对2型糖尿病患者阻生牙拔除术后干槽症发生的影响。方法:选择2016年1月-2017年1月发生阻生牙的2型糖尿病患者85例,按随机数字表法分为A组(29例)、B组(25例)和C组(31例)。所有患者均采用专用涡轮钻法拔牙后,A组患者创面部位填塞康复新液+吸收性明胶海绵;B组患者创面部位填塞疮疡灵-康复新液明胶海绵复合制剂;C组患者创面部位直接填塞纱布而不使用药物。所有患者术后常规进行抗感染治疗5~7 d。比较3组患者阻生牙拔除时间,术后7 d牙槽窝肉芽组织覆盖完整率、干槽症发生率,术后其他并发症发生率,治疗费用及满意度评分。结果:3组患者阻生牙拔除时间、治疗费用比较,差异均无统计学意义(P>0.05)。术后7 d,牙槽窝肉芽组织覆盖完整率、满意度评分均为B组>A组>C组,干槽症发生率均为B组<A组<C组,组间两两比较差异均有统计学意义(P<0.05)。术后A、B组患者出血、疼痛、肿胀、张口受限等其他并发症的总发生率均显著低于C组,差异均有统计学意义(P<0.05);但A、B组比较差异无统计学意义 (P>0.05)。结论:康复新液联合疮疡灵、明胶海绵可有效提高2型糖尿病患者阻生牙拔除术后牙槽窝肉芽组织覆盖完整度,降低术后干槽症及其他并发症的发生风险,且不增加患者的经济负担,患者满意度较高。
ABSTRACT: OBJECTIVE: To investigate the effects of Kangfuxin solution combined with Chuangyangling and gelatin sponge on dry socket disease in patients with type 2 diabetes mellitus after the extraction of impacted teeth. METHODS: A total of 85 patients with impacted teeth and type 2 diabetes mellitus during Jan. 2016-Jan. 2017 were divided into group A (29 cases), B (25 cases), C (31 cases) according to random number table. All patients were treated with turbine drill method; in group A, Kangfuxin solution+Absorbable gelatin sponge was used to fill the wound site; in group B, Chuangyangling+compound preparation of Kangfuxin solution and gelatin sponge were used to fill the wound site; in group C, the wounds were filled with gauze but without any drugs. All patients received routine anti-infective treatment after surgery for 5-7 d. The time of impacted teeth extraction was observed in 3 groups; granulation tissue coverage integrity rate of tooth socket and the incidence of dry socket disease 7 d after surgery, the incidence of other postoperative complications, treatment cost, satisfaction scores were also comparod. RESULTS: There was no statistical significance in the time of impacted teeth extraction or treatment cost among 3 groups (P>0.05). Seven days after surgery, granulation tissue coverage integrity of tooth socket and satisfaction scores were in descending order: group B>group A>group C; the incidence of dry sockets were in ascending order: group B<group A<group C, with statistical significance (P<0.05). The incidence of other postoperative complications as bleeding, pain, swelling, limitation of mouth opening in group A and B were significantly lower than group C, with statistical significance (P<0.05). There were no statistical significance between group A and B (P>0.05). CONCLUSIONS: Kangfuxin solution combined with Chuangyangling and gelatin sponge can effectively increase granulation tissue coverage integrity of tooth socket, and reduce the incidence of dry socket disease and other postoperative complications in patients with type 2 diabetes mellitus, but do not increase economic burden of patients and obtain high patient satisfaction.
期刊: 2018年第29卷第4期
作者: 张则明,邬志锋,季佳,王桥,徐岩,周辰,许远志
AUTHORS: ZHANG Zeming,WU Zhifeng,JI Jia,WANG Qiao,XU Yan,ZHOU Chen,XU Yuanzhi
关键字: 康复新液;疮疡灵;明胶海绵;2型糖尿病;阻生牙拔除术;干槽症
KEYWORDS: Kangfuxin solution; Chuangyangling; Gelatin sponge; Type 2 diabetes mellitus; Extraction of impacted teeth; Dry socket disease
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