实施国家基本药物制度对我国基层医疗卫生机构激素类药物使用率影响的Meta 分析
x

请在关注微信后,向客服人员索取文件

篇名: 实施国家基本药物制度对我国基层医疗卫生机构激素类药物使用率影响的Meta 分析
TITLE:
摘要: 目的:系统评价国家基本药物制度的实施对我国基层医疗卫生机构激素类药物使用率的影响。方法:计算机检索中国期刊全文数据库(CJFD)、 万方数据库、中文科技期刊数据库(VIP),收集国家基本药物制度实施前后激素类药物使用情况的研究文献,提取资料并按照Cochrane系统评价员手册5.1.0版评价文献质量后,采用Stata 13.0 统计软件对使用率数据进行Meta分析。结果:最终纳入20篇文献。Meta 分析结果显示,实施国家基本药物制度后激素类药物使用率显著低于实施前,差异有统计学意义[RD=-0.03,95%CI(-0.05,-0.02), P<0.001]。对不同地区实施国家基本药物制度前后激素类药物使用率按照东、中、西部进行亚组分析结果显示,东部地区实施国家基本药物制度后激素类药物使用率显著低于实施前,差异有统计学意义[RD=-0.06,95%CI(-0.09,-0.03),P=0.001],中部地区[RD=-0.02,95%CI(-0.06,0.02),P=0.235]、西部地区[RD=-0.01,95%CI(-0.02,0),P=0.122]实施国家基本药物制度前后激素类药物使用率比较,差异均无统计学意义。结论:国家基本药物制度的实施在一定程度上减少了我国基层医疗卫生机构激素类药物的使用,且东部地区实施效果较中、西部地区更明显。
ABSTRACT: OBJECTIVE: To evaluate the effects of the implementation of National Essential Medicine System on the utilization rate of hormone drugs in primary medical institutions in China systematically. METHODS: Retrieved from CJFD, Wanfang database and VIP, the literatures about the use of hormone drugs were collected before and after the implementation of National Essential Medicine System. Meta-analysis was performed by using Stata 13.0 software after utilization rate data extraction and quality evaluation with Cochrane system evaluator manual 5.1.0. RESULTS: A total of 20 literatures were included. Results of Meta-analysis showed that utilization rate of hormone drugs after the implementation of National Essential Medicine System was significantly lower than before implementation, with statistical significance [RD=-0.03,95%CI (-0.05,-0.02),P<0.001]. Results of subgroup Meta-analysis of utilization rate of hormone drugs in different areas before and after the implementation of National Essential Medicine System showed that the utilization rate of hormone drugs in eastern areas was significantly lower after the implementation of National Essential Medicine System than before [RD=-0.06,95%CI(-0.09,-0.03),P=0.001] with statistical significance. There was no statistical significance in the utilization rate of hormone drugs in middle area [RD=-0.02,95%CI(-0.06,0.02),P=0.235] or western area [RD=-0.01,95%CI(-0.02,0),P=0.122] before and after the implementation of National Essential Medicine System. CONCLUSIONS: The implementation of National Essential Medicine System reduces the utilization of hormone drugs in primary medical institutions. The effect of the eastern area is more obvious than in middle and western area.
期刊: 2018年第29卷第2期
作者: 田燕,蒋易芬,胡健培,蒲川,张力
AUTHORS: TIAN Yan,JIANG Yifen,HU Jianpei,PU Chuan,ZHANG Li
关键字: 国家基本药物制度;基层医疗卫生机构;激素类药物;使用率;Meta分析
KEYWORDS: National Essential Medicine System; Primary medical institution; Hormone drug; Utilization rate; Meta-analysis
阅读数: 395 次
本月下载数: 9 次

* 注:未经本站明确许可,任何网站不得非法盗链资源下载连接及抄袭本站原创内容资源!在此感谢您的支持与合作!