正交试验优化复方胃炎胶囊中药材的水提工艺
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篇名: 正交试验优化复方胃炎胶囊中药材的水提工艺
TITLE:
摘要: 目的:优化复方胃炎胶囊中药材的水提工艺。方法:采用正交试验,以干膏中芍药苷含量、丹酚酸B含量与干膏质量的综合评分为评价指标,考察加水量、煎煮时间和煎煮次数对水提工艺的影响,并进行验证试验。结果:优化的水提工艺为煎煮3次、每次120 min、每次加10倍量水;验证试验中综合评分平均值为909.19(RSD=1.84%,n=3)。结论:优化的水提工艺稳定、可行,可用于复方胃炎胶囊中各药材的提取。
ABSTRACT: OBJECTIVE: To optimize the water extraction technology for the medicinal materials in Compound gastritis capsule. METHODS: Orthogonal test was adopted. Using the comprehensive score of contents of paeoniflorin, salvianolic acid B and weight of dry extract as evaluation index, effects of adding water amount, decoction time and times on water extraction technology were investigated, and verification test was conducted. RESULTS: Optimized water extraction technology was as follows as decocting for 3 times, 120 min each time and adding 10-fold water each time. In verification test, average comprehensive score was 909.19 (RSD=1.84%, n=3). CONCLUSIONS: Optimized water extraction technology is stable and feasible, and can be used for the water extraction for each medicinal material in Compound gastritis capsule.
期刊: 2017年第28卷第31期
作者: 郑姣妮,刘玲,何道惠
AUTHORS: ZHENG Jiaoni,LIU Ling,HE Daohui
关键字: 复方胃炎胶囊;正交试验;提取工艺;芍药苷;丹酚酸B
KEYWORDS: Compound gastritis capsule; Orthogonal test; Extraction technology; Paeoniflorin; Salvianolic acid B
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