广西9家“三甲”医院头孢菌素类抗菌药物对胆囊结石切除术患者住院费用和住院天数的影响分析
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篇名: 广西9家“三甲”医院头孢菌素类抗菌药物对胆囊结石切除术患者住院费用和住院天数的影响分析
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摘要: 目的:考察头孢菌素类抗菌药物对胆囊结石切除术患者住院费用和住院天数的影响,为其临床应用提供参考。方法:收集广西9家“三甲”医院2013-2014年入院, 经手术治疗后已出院的胆囊结石患者资料,共1 866例。采用SPSS 22.0软件对胆囊结石切除术患者的住院费用和住院天数的影响因素进行分析。结果:多因素分析结果显示,抗菌药物、医院、年龄、手术类型、出院诊断病种数均为明显影响住院费用和住院天数的因素(均为P<0.01)。按照住院费用,抗菌药物被分成1~4档,第1档仅含头孢呋辛(9 454元),第2档含非头孢菌素类(16 199元)和五水头孢唑林(17 241元),第3档含头孢他啶(20 716元)、其他头孢菌素类(21 046元)和头孢噻肟舒巴坦(22 724元),第4档含头孢噻肟舒巴坦(22 724元)、头孢哌酮舒巴坦(23 688元)、头孢西丁(24 685元)和头孢地嗪(24 698元);按照住院天数,抗菌药物同样被分成1~4档,第1档仅含非头孢菌素类(7.61 d),第2档含头孢呋辛(8.94 d)和五水头孢唑林(9.78 d),第3档含头孢西丁(13.39 d)、头孢地嗪(13.44 d)、其他头孢菌素类(14.32 d)和头孢他啶(14.60 d),第4档含头孢哌酮舒巴坦(16.03 d)和头孢噻肟舒巴坦(16.91 d)。档数越大其对应的住院费用越高或住院天数越长,不同档次之间差异有统计学意义(P<0.05),同档次内则差异无统计学意义(P>0.05)。结论:头孢菌素类抗菌药物品种的选择可以明显影响胆囊结石切除术患者的住院费用和住院天数,临床可根据本地医疗资源和患者要求综合考虑。
ABSTRACT: OBJECTIVE: To investigate the influence of cephalosporins antibiotics on cost and length of hospital stay in patients underwent gallbladder calculus resection, and to provide reference for drug use in clinic. METHODS: A total of 1 866 patients underwent gallbladder calculus resection were collected from 9 third grade class A hospitals in Guangxi during 2013-2014. SPSS 22.0 software was adopted to analyze cost and length of hospital stay in patients underwent gallbladder calculus resection. RESULTS: Multi-factor analysis showed that the factors which significantly affected the cost and length of hospital stay were antibiotics, hospitals, age, surgery types and disease species (all P<0.01). The antibiotics were divided into the subset 1-4 according to the cost of hospital stay: the subset 1 only contained cefuroxime (9 454 yuan); the subset 2 contained noncephalosporins (16 199 yuan) and cefazolin pentahydrate (17 241 yuan); the subset 3 contained ceftazidime (20 716 yuan), other cephalosporins (21 046 yuan) and cefotaxime sulbactam (22 724 yuan); subset 4 contained cefotaxime sulbactam (22 724 yuan), cefoperazone sulbactam (23 688 yuan), cefoxitin (24 685 yuan) and cefodizime (24 698 yuan). The antibiotics were also divided into the subset 1-4 according to the length of hospital stay: the subset 1 only contained noncephalosporins (7.61 d); the subset 2 contained cefuroxime (8.94 d) and cefazolin pentahydrate (9.78 d); the subset 3 contained cefoxitin (13.39 d), cefodizime (13.44 d), other cephalosporins (14.32 d) and ceftazidime (14.60 d); the subset 4 included cefoperazone sulbactam (16.03 d) and cefotaxime sulbactam (16.91 d). The higher the subset numbers, the higher the cost of hospital stay or the longer the length of hospital stay; there were statistical differences among different subsets (P<0.05), while there was no statistical difference among the same subsets (P>0.05). CONCLUSIONS: Cephalosporins antibiotics can significantly influence the cost and length of hospital stay in patients underwent gallbladder calculus resection. Antibiotics selection canbe considered comprehensively according to local medical resources and the patients’demands.
期刊: 2017年第28卷第20期
作者: 杨玲玲,刘天奇,叶溪,莫志江
AUTHORS: YANG Lingling,LIU Tianqi,YE Xi,MO Zhijiang
关键字: 胆囊结石;住院费用;住院天数;头孢菌素类抗菌药物
KEYWORDS: Gallbladder calculus; Cost of hospital stay; Length of hospital stay; Cephalosporins antibitoics
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