他莫昔芬超说明书用于促排卵的分析与管理
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篇名: 他莫昔芬超说明书用于促排卵的分析与管理
TITLE:
摘要:

目的:对他莫昔芬用于促排卵的合理性进行分析,为规范他莫昔芬超说明书用药提供参考。方法:以“他莫昔芬”“促排

卵”“多囊卵巢综合征”“Tamoxifen”“Ovulation induction”“ Polycystic ovarian syndrome”等为关键词,组合查询中国知网、万方、

PubMed等数据库,检索截止时间为2015 年7 月,对他莫昔芬超说明书用于促排卵的相关文献进行分析与总结。结果:共查到文献

58 篇,选择其中研究他莫昔芬促排卵效果的临床试验或系统评价的文献,得到国内外有效文献11 篇,均肯定他莫昔芬用于促排卵

的临床效果。参考《多囊卵巢综合征的诊断和治疗专家共识》,我院药事委员会审核同意他莫昔芬超说明书用于促排卵,并制订了

相应的使用规范。结论:规范管理他莫昔芬超说明书用药,可更好地维护医师和患者的权益。

ABSTRACT:

OBJECTIVE:To analyze the rationality of tamoxifen for ovulation induction,and to provide reference for the standardization

of off-label use of tamoxifen. METHODS:Taking“tamoxifen”,“ovulation induction”and“polycystic ovarian syndrome”

as keywords,relevant literatures about off-label use of tamoxifen for ovulation induction were analyzed and summarized by

a search of CNKI,Wanfang database,PubMed database up to July 2015. RESULTS:58 literatures were searched,among which

clinical trial or systematic review about the effect of tamoxifen on ovulation induction were selected. 11 valid literatures were collected

to confirm clinical efficacy of tamoxifen for ovulation induction. Referring to Diagnosis and Treatment of Polycystic Ovary

Syndrome:An Expert Consensus,pharmaceutical affairs council of our hospital had agreed to off-label use of tamoxifen for induction

ovulation,and formulated the standard of off-label use of tamoxifen. CONCLUSIONS:Standard management of off-label use

of tamoxifen could be better protect the rights both of patient and doctor

期刊: 2016年第27卷第1期
作者: 吉柳,武文慧,阎丽丽,李晓军
AUTHORS: JI Liu,WU Wenhui,YAN Lili,LI Xiaojun
关键字: 超说明书用药;他莫昔芬;多囊卵巢综合征;促排卵;文献分析;规范管理
KEYWORDS: Off-label drug use;Tamoxifen;Polycystic ovarian syndrome;Ovulation induction;Literature analysis;Standard
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