左氧氟沙星联合润肺膏治疗慢性支气管炎的疗效分析
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篇名: 左氧氟沙星联合润肺膏治疗慢性支气管炎的疗效分析
TITLE:
摘要: 目的:探讨左氧氟沙星联合润肺膏治疗慢性支气管炎的疗效和安全性。方法:回顾性分析154例慢性支气管炎患者资料,按用药不同分为对照组(76例)和观察组(78例)。对照组患者口服左氧氟沙星片0.2,bid+盐酸氨溴索口服溶液10 ml,bid。观察组患者口服左氧氟沙星片0.2 g,bid+润肺膏15 g,温开水冲服,tid。两组患者连用左氧氟沙星片7 d后停药,对照组患者继续服用盐酸氨溴索溶液7 d,剂量保持不变;观察组患者继续服用润肺膏7 d,剂量保持不变。两组疗程均为14 d。观察两组患者临床疗效、临床症状(发热、咳嗽、咳痰、气喘)持续时间及不良反应发生情况。结果:观察组患者总有效率显著高于对照组,咳嗽、咳痰持续时间、气喘持续时间均显著短于对照组,差异均有统计学意义(P<0.05)。两组患者发热持续时间、不良反应发生率比较差异均无统计学意义(P>0.05)。结论:左氧氟沙星联合润肺膏治疗慢性支气管炎的疗效显著,可缩短患者临床症状持续时间,且不增加不良反应的发生。
ABSTRACT: OBJECTIVE: To investigate the clinical efficacy and safety of Runfei cream combined with levofloxacin in the treatment of chronic bronchitis. METHODS: Data of 154 patients with chronic bronchitis were retrospectively collected and divided into observation group (78 cases) and control group (76 cases). Control group orally received Levofloxacin tablet, 0.2 g, bid+ambroxol hydrochloride oral solution 10 ml,bid. Observation group received Levofloxacin tablet, 0.2 g, bid+Runfei cream 15 g with warm water, tid. All patients stopped taking drugs after 7 d of Levofloxacin tablet, observation group continued to take Runfei cream for 7 d and control group continued to take ambroxol hydrochloride oral solution for 7 d with the same dose . Clinical efficacy, duration of clinical symptoms (duration of fever,cough,expectoration,asthma)and the incidence of adverse reactions in 2 groups were compared.The courses of 2 groups were 14 d.RESULTS: The total effective rate in observation group was significantly higher than control group, cough and expectoration time and asthma time were significantly lower than control group, with significant differences (P<0.05); and there was no significant difference in the duration of fever and the incidence of adverse reactions (P>0.05). CONCLUSIONS: Levofloxacin combined with Runfei cream has good efficacy in the treatment of chronic bronchitis, it can shorten duration of clinical symptoms, and do not increase the incidence of adverse reactions.
期刊: 2016年第27卷第33期
作者: 刘春花,周志愉,孙法莹,肖纯
AUTHORS: LIU Chunhua,ZHOU Zhiyu,SUN Faying,XIAO Chun
关键字: 润肺膏;左氧氟沙星;氨溴索;慢性支气管炎;疗效;安全性
KEYWORDS: Runfei cream; Levofloxacin; Ambroxol; Chronic bronchitis; Efficacy; Safety
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