临床药师参与1例溺水后肺部感染合并脑脓肿患儿的抗感染治疗实践
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篇名: 临床药师参与1例溺水后肺部感染合并脑脓肿患儿的抗感染治疗实践
TITLE:
摘要: 目的:探讨临床药师在复杂感染患儿抗感染治疗中的作用。方法:临床药师参与1例因溺水致肺部感染及脑脓肿患儿的治疗过程,协助医师调整抗菌药物治疗方案,并根据病原菌特点、治疗效果及药品不良反应,先后提出抗革兰氏阳性和阴性菌药物调整、万古霉素剂量调整、万古霉素不良反应及其处理、抗侵肺巴斯德菌药物的选择、加强抗真菌感染治疗等建议。结果:医师部分采纳临床药师建议,经过5次抗感染治疗方案的调整,患儿肺部及脑部的感染得到了有效控制,不良反应症状消失。结论:临床药师参与复杂感染患儿的治疗过程,结合患儿病原学检查结果,协助医师制订安全、有效的抗感染方案,及时处理药品不良反应,并积极开展抗菌药物疗效评估及药学监护,对患儿的治疗起到了积极的作用。
ABSTRACT: OBJECTIVE: To explore the role of clinical pharmacists participating in anti-infective treatment for a child with complex infection. METHODS: Clinical pharmacists participated in treatment process of one child with pulmonary infection and brain abscess after a near-drowning incident, assisted physicians to adjust antibiotics therapy plan, and put several suggestions as the adjustment of anti-gram-positive and anti-gram-negtive bacterium drugs, the dosage adjustment of vancomycin, vancomycin-induced ADR and disposal, the selection of anti-Pasteurella pneumotropica drugs, the enhancement of anti-fungal infection therapy, according to pathogen characteristics, treatment effect and ADR. RESULTS: Physicians partly adopted the advice of clinical pharmacists,  the child’s pulmonary and brain infection were controlled effectively and ADR disappeared after 5 times of adjusting anti-infective the rapy plan. CONCLUSIONS: Clinical pharmacists participate in the treatment process of one child with complex infection, and assist physicians to formulate safe and effective anti-infective plan according to the results of etiological examination; dispose ADR timely and carry out efficacy evaluation of antibiotics and pharmaceutical care, that can give positive effects on patient treatment.
期刊: 2016年第27卷第26期
作者: 何翠瑶,王刚,樊继山,吴青,贾运涛,张艳
AUTHORS: HE Cuiyao,WANG Gang,FAN Jishan,WU Qing,JIA Yuntao,ZHANG Yan
关键字: 临床药师;肺部感染;脑脓肿;溺水;药学监护
KEYWORDS: Clinical pharmacist; Pulmonary infection; Brain abscess; Near-drowning; Pharmaceutical care
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