280例乳腺癌患者内分泌治疗用药依从性分析
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篇名: 280例乳腺癌患者内分泌治疗用药依从性分析
TITLE:
摘要: 目的:为提高乳腺癌患者用药依从性提供参考。方法:抽取某院乳腺科化疗病区2015年9-11月曾行内分泌治疗的晚期乳腺癌住院患者280例,采用问卷调查和现场访谈相结合的方式,对其内分泌治疗的用药依从性及影响因素、内分泌治疗药物致不良反应等情况进行调查分析。结果:280例患者中,用药依从性良好、一般及较差的患者分别有161例(57.5%)、64例(22.9%)和55例(19.6%);其用药依从性主要受“认为疾病已控制(27.2%)”“药品不良反应(22.4%)”“忘记服药(21.1%)”等因素的影响;内分泌治疗药物常见的药品不良反应包括潮热、情绪异常和关节痛等。结论:临床药师尤其是专科临床药师应充分发挥自身专业优势,加强患者的用药教育,积极参与查房和随访工作,提高乳腺癌患者内分泌治疗的用药依从性。
ABSTRACT: OBJECTIVE: To provide reference for improving the breast cancer patients’medication compliance. METHODS: 280 inpatients with advanced breast cancer who had received endocrine therapy in a hospital ward of chemotherapy of breast from Sept. to Nov. 2015 were selected, questionnaires was combined with on-site interview to investigate and analyze the medication compliance, influential factors and adverse reactions induced by endocrine drugs. RESULTS: Among the 280 patients, 161 (57.5%) showed good medication compliance, 64 (22.9%) were general and 55 (19.6%) were poor; its medication compliance were mainly affected by “wrong understanding on disease control (27.2%)”“adverse drug reactions (22.4%)”“forgetting taking medicines (21.1%)”; the common adverse reactions of endocrine therapy included hot flashes, mood disorders and joint pain. CONCLUSIONS: Clinical pharmacists, especially the specialists should give full play to their own professional advantage, strengthen patient medication education, actively participate ward round and follow-up, improve breast cancer patients’compliance on endocrine therapy.
期刊: 2016年第27卷第26期
作者: 杜娟,赵秀莉,张文周
AUTHORS: DU Juan,ZHAO Xiuli,ZHANG Wenzhou
关键字: 临床药师;乳腺癌;内分泌治疗;用药依从性
KEYWORDS: Clinical pharmacists; Breast cancer; Endocrine therapy; Medication compliance
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